Research Antibiotics, Tedizolid, 50mg

Tedizolid, 50 mg. Tedizolid Phosphate is an oxazolidone antibiotic. It is a phosphate ester prodrug of Tedizolid, the active compound. It is bacteriostatic against Gram-positive organisms.

• Category: Cancer Research
• CAS Number: 856867-55-5
• Molecular Formula: C₁₇H₁₆FN₆O₆P
• Molecular Weight: 450.32 g/mol
• Mechanism of Action: Tedizolid binds to the 23S rRNA of the 50S ribosomal subunit, preventing the formation of the 70S initiation complex and inhibiting protein synthesis.
• Storage Conditions: -20°C
• Spectrum: Effective against Gram-positive bacteria including MRSA and VRE, and linezolid-resistant strains

Microbiology Applications

Tedizolid inhibited all 28 isolates of penicillin-resistant Streptococcus pneumoniae using an in vitro mouse model with 0.25 µg/mL, which was 4-fold more potent than Linezolid (Choi et al, 2012).

Specifications

• Form: Powder
• Appearance: White to off-white powder
• Source: synthetic

References

Choi S, Im W, and Bartizal K (2012) Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Sep;56(9):4713-7 PMID 22713339 Kisgen JJ, Mansour H, Unger NR, Childs LM (2014) Tedizolid: a new oxazolidinone antimicrobial. Am. J. Health Syst. Pharm. 71(8):621-33 PMID 24688035 Rybak JM, Marx K, Martin CA (2014) Early experience with tedizolid: Clinical efficacy, pharmacodynamics, and resistance. Pharmacother. 34(11):1198-208 PMID 25266820

Available Documents

• SDS-EU
• SDS
• Product Data Sheet

Made by an ISO 9001:2015 certified antibiotic manufacturer focused on creating antibiotics through fermentation.

By removing contamination and streamlining gene selection, these research antibiotics help scientists make discoveries in cell/plant biology, microbiology, virology, stem cell therapy, and cancer research. Specializing in the pharmaceutical and biotech research sectors.

These products are specifically designed for research use and are not approved for human or animal consumption. Not FDA approved.

Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not ship to a registered laboratory or research facility.

Please note: This product is not returnable.