Research Antibiotics, Virginiamycin, 95%+, 500 mg

Virginiamycin, >95%, 500 mg. Virginiamycin is a streptogramin, and a mixture of Virginiamycin M1 and Virginiamycin S1. The commercial mixture is 75% Virginiamycin M1 and 25% Virginiamycin S1, along with less abundant S analogs. The mixture can be used to reduce contaminating bacteria during yeast fermentation for bioethanol production. Virginiamycin is soluble in DMSO and DMF.

• Family: Microbiology
• CAS Number: 11006-76-1
• Molecular Formula: C28H35N3O7 (for M1), C43H49N7O10 (for S1)
• Molecular Weight: 525.6 (for M1); 823.9 (for S1)
• Mechanism of Action: Virginiamycin inhibits protein synthesis, targeting the 50S ribosome and inducing a conformational change at the peptidyl transferase center. Protein synthesis is inhibited in both actively growing and static bacterial cells.
• Storage Conditions: -20°C
• Spectrum: Gram-positive bacteria, such as Lactobacillus spp.

Microbiology Applications

Virginiamycin is used in bioproduction, specifically to reduce contaminating bacteria when fermenting yeast for bioethanol production.

Specifications

• Form: Powder
• Color: White powder
• Source: Streptomyces virginiae

References

Bischoff KM, Liu S, Leathers TD, Worthington RE and Rich JO (2008) Modeling bacterial contamination of fuel ethanol fermentation. Biotechnology. Bioengineering. 103(1):117-122 Crooy P and De Neys RJ (1972) Virginiamycin: nomenclature. Antibiotic. 25:371 Ogata K et al (1978) A new species of Streptomyces producing Virginiamycin family antibiotics. J. Antibiotic. 31: 1313 Parfait R and Cocito C (1980) Lasting damage to bacterial ribosomes by reversibly bound Virginiamycin M. Proc. Natl. Acad. Sci. USA 77(9):5492-5496 Rich JO et al (2011) Rapid evaluation of the antibiotic susceptibility of fuel ethanol contaminant biofilms. Bioresour. Technol. 102 (2):1124-1130.

Available Documents

• SDS-EU
• SDS
• Product Data Sheet

Made by an ISO 9001:2015 certified antibiotic manufacturer focused on creating antibiotics through fermentation.

By removing contamination and streamlining gene selection, these research antibiotics help scientists make discoveries in cell/plant biology, microbiology, virology, stem cell therapy, and cancer research. Specializing in the pharmaceutical and biotech research sectors.

These products are specifically designed for research use and are not approved for human or animal consumption. Not FDA approved.

Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not ship to a registered laboratory or research facility.

Please note: This product is not returnable.