TTF-1 & Cytokeratin 5 Multiplex Cocktail; Clones 8G7G3/1 & EP42 (Ready-To-Use), 2 ml

TTF-1 & Cytokeratin 5 Multiplex Cocktail; Clones 8G7G3/1 & EP42 (Ready-To-Use), 2 mL.

• Species: Mouse and Rabbit
• Designation: Mouse Monoclonal & Rabbit Monoclonal
• Clones: 8G7G3/1 & EP42
• Isotype: IgG1 & IgG
• Species Reactivity: Human. Others not tested.
• Positive Control: Adenocarcinoma of the Lung or Thyroid for TTF-1. Skin for normal tissue and Mesothelioma for abnormal tissue for Cytokeratin 5.
• Principle: Multiplex IHC staining allows simultaneous testing of two or more analytes on a single tissue section utilizing different colors for each antigenic target.

Specificity: This antibody reacts with TTF-1 protein found in adenocarcinomas of the lung and tumors originating in the thyroid. TTF-1 positive cells are found in Type II pneumocytes and Clara cells in the lung. In the thyroid, follicular and parafollicular cells are positive. In lung cancers, Adenocarcinomas are usually positive, while Squamous Cell Carcinomas and Large Cell Carcinomas are rarely positive. In addition, Small-Cell Carcinomas (of any primary site) are usually positive. Cytokeratin 5 is expressed in many non-keratinizing stratified squamous epithelia including: basal epithelia, hair follicles, trachea, tongue mucosa, as well as basal cells in prostate glands and myoepithelial cells in mammary glands. Cytokeratin 5 protein is also found in most epithelial and bispasic mesotheliomas, large cell carcinoma and pulmonary squamous cell carcinomas. This Multiplex cocktail of TTF-1 and Cytokeratin 5 produces two-color high contrast staining for differentiating primary adenocarcinoma of the Lung from Metastatic Carcinomas of the breast and Malignant Mesothelioma.

• Volume: 2 mL
• Storage: 2°C- 8°C
• Download: Instructions For Use
• MSDS: Material Safety Data Sheet

Antibodies > Multiplex Cocktail

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These chemicals are for professional manufacturing, research laboratories and industrial / commercial usage only. Not for medical or consumer use. We currently cannot ship this product to doctor offices, pharmacies, medical facilities, veterinarians or residences. All orders are verified prior to shipment. Orders shipping to consumers or medical facilities will be canceled.

Please note: This product is not returnable. Chemicals cannot be expedited.