Tris(Hydroxymethyl) Aminomethane ACS Reagent, 99.8% 500 grams

Tris(Hydroxymethyl) Aminomethane ACS Reagent, 99.8% 500 grams

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500 gram


Due to a dramatic reduction in supply, stock numbers cannot be guaranteed. All purchases will be followed by an order confirmation with estimated ship date and you will be notified if stock is unavailable. All orders for healthcare products placed after January 24, 2020 are non-cancellable and non-returnable. Thank you for your continued cooperation and partnership.

Tris(Hydroxymethyl) Aminomethane Acs Reagent 99.8% 500 Gram

Synonym: 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

  • CAS Number 77-86-1
  • Linear Formula NH2C(CH2OH)3
  • Molecular Weight 121.14
  • Beilstein/REAXYS Number 741883
  • EC Number 201-064-4
  • MDL number MFCD00004679
  • PubChem Substance ID 24855244
  • NACRES NA.25
grade ACS reagent



≤0.005% insolubles
≤2% water

useful pH range 7 - 9
pKa (25 °C) 8.1
bp 219-220 °C/10 mmHg (lit.)
mp 167-172 °C (lit.)
cation traces

Fe: ≤5 ppm
heavy metals (as Pb): ≤5 ppm

absorption passes test

General description

Tris(hydroxymethyl)aminomethane is mainly required for preparation of buffers at physiological range of 7.3 to 7.5. The prepared buffers are compatible with biological fluids. It is of importance to laboratories as a standard pH solution.


Tris(hydroxymethyl)aminomethane has been used as a buffer solution for lactate dehydrogenase assay, in situ hybridization procedure and protein extraction from cells.

Safety Information

RIDADR NONH for all modes of transport
WGK Germany 1
RTECS TY2900000


Safety Data Sheet


Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not work for, and ship to, a registered laboratory or research facility. Not for topical applications. An official Declaration of Use form may be required.

Most chemicals cannot be expedited.

WARNING: This product can expose you to chemicals which are known to the State of California to cause cancer and reproductive harm. Prop 65 Warning

Please note: This product is not returnable.

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