Sigma-Aldrich
Chaps Hydrate Bioxtra 98% TLC 5 grams
- Part Number:
- MIL-C5070-5G
- Lead Time:
- 2-4 weeks
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- Quantity:
- each
- Size:
- 5 grams
- Style:
- chemical
- DOT Rated:
- HazMat Transport Fee Required
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Description
Chaps Hydrate Bioxtra ≥98% TLC 5 Gram
Synonym: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, CHAPS
- CAS Number 331717-45-4
- Empirical Formula (Hill Notation) C32H58N2O7S · xH2O
- Molecular Weight 614.88 (anhydrous basis)
- PubChem Substance ID 24892750
- NACRES NA.21
| Quality Level | 400 |
| description | zwitterionic |
| product line | BioXtra |
| assay | ≥98% (TLC) |
| mol wt | 614.88 g/mol (anhydrous basis) |
| application(s) | protein purification: suitable |
| protein quantification: suitable | |
| impurities | ≤0.001% Phosphorus (P) |
| ≤0.1% Insoluble matter | |
| ign. residue | ≤0.1% |
| mp | 157 °C (dec.) (lit.) |
| solubility | H2O: 0.1 M, clear, colorless |
| anion traces | chloride (Cl-): ≤0.05% |
| cation traces | Al: ≤0.0005% |
| Ca: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Mg: ≤0.0005% | |
| NH4+: ≤0.05% | |
| Na: ≤0.005% | |
| Pb: ≤0.001% | |
| Zn: ≤0.0005% | |
| SMILES string | O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C |
| InChI | 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1 |
| InChI key | SJCUTFKCLFLIFE-JWTJKVBLSA-N |
General description
CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.
Application
• 10mM CHAPS detergent has been used in the process of ion-exchange chromatography for improved purification.
• 0.5 w/v of CHAPS is a component of high salt buffer in protein purification alongside HEPES, NaCl and EDTA.
• HEPES buffer has been used as lysis buffer in immunoprecipitation, supplemented with 1% CHAPS.
GHS08
Signal word Danger
Hazard statements H360D
Precautionary statements P201-P202-P280-P308 + P313-P405-P501
RIDADR NONH for all modes of transport
WGK Germany 1
Documents
Warnings
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WARNING: This product can expose you to chemicals which are known to the State of California to cause cancer and reproductive harm. Prop 65 Warning
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