Sigma-Aldrich
Trifluoroacetic Acid, Puriss. P.A. For HPLC 99% GC 250 mL
- Part Number:
- MIL-91707-250ML
- Lead Time:
- 2-4 weeks
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- Quantity:
- each
- Size:
- 250 ml / 8 ounce
- Style:
- chemical
- DOT Rated:
- HazMat Transport Fee Required
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Description
Trifluoroacetic Acid Puriss. P.A. For HPLC ≥99.0% GC 250mL
Synonym: TFA
- CAS Number 76-05-1
- Linear Formula CF3COOH
- Molecular Weight 114.02
- Beilstein/REAXYS Number 742035
- EC Number 200-929-3
- MDL number MFCD00004169
- PubChem Substance ID 329770068
- NACRES NA.21
| grade | for HPLC |
| vapor density | 3.9 (vs air) |
| vapor pressure | 97.5 mmHg ( 20 °C) |
| grade | puriss. p.a. |
| assay | ≥99.0% (GC) |
| impurities | ≤0.05% water |
| refractive index | n20/D 1.3 (lit.) |
| bp | 72.4 °C (lit.) |
| mp | −15.4 °C (lit.) |
| solubility | water: soluble |
| density | 1.489 g/mL at 20 °C (lit.) |
| λ | 1 cm path, H2O reference |
| UV absorption | λ: 260 nm Amax: 0.9 |
| λ: 270 nm Amax: 0.1 | |
| λ: 280 nm Amax: 0.05 | |
| λ: 290 nm Amax: 0.04 | |
| λ: 300 nm Amax: 0.03 | |
| λ: 320 nm Amax: 0.025 | |
| suitability | corresponds to standard for RP gradient test |
| SMILES string | OC(C(F)(F)F)=O |
| InChI | 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) |
| InChI key | DTQVDTLACAAQTR-UHFFFAOYSA-N |
General description
Trifluoroacetic acid (TFA) is a fluorinated acetic acid. It is widely used as trifluoromethylating reagent for trifluoromethylation of aromatic compounds.
Application
Trifluoroacetic acid (TFA) may be used in the following studies:
• Preparation of TFA reagent for the estimation of serum vitamin A.
• To compose the binary solvent system for the isolation of large denatured peptides by reverse phase high performance liquid chromatography.
• A mobile-phase additive for liquid chromatography-mass spectrometry (LC-MS) analysis.
• Preparation of artemisinin under optimized reaction conditions.
GHS05, GHS07
Signal word Danger
Hazard statements H314-H332-H412
Precautionary statements P273-P280-P305 + P351 + P338-P310
RIDADR UN 2699 8 / PGI
WGK Germany 2
RTECS AJ9625000
Flash Point(F) >212 °F
Flash Point(C) >100 °C
Documents
Warnings
Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not work for, and ship to, a registered laboratory or research facility. Not for topical applications. An official Declaration of Use form may be required.
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WARNING: This product can expose you to chemicals which are known to the State of California to cause cancer and reproductive harm. Prop 65 Warning
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