CA19-9; Clone 121SLE (Ready-To-Use), 7 mL.
- Species: Mouse
- Clone: 121SLE
- Isotype: IgM, Kappa
- Species Reactivity: Human Cellular Localization: Lumenal surface and cytoplasm.
Specificity: CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.
Antibodies > Monoclonal Ready-to-Use
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These chemicals are for professional manufacturing, research laboratories and industrial / commercial usage only. Not for medical or consumer use. We currently cannot ship this product to doctor offices, pharmacies, medical facilities, veterinarians or residences. All orders are verified prior to shipment. Orders shipping to consumers or medical facilities will be canceled.
Please note: This product is not returnable. Chemicals cannot be expedited.