N N-Dimethylacetamide, ReagentPlus® 500mL, case/6

N N-Dimethylacetamide, ReagentPlus® 500mL, case/6

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500 mL / 16 ounce


Due to a dramatic reduction in supply, stock numbers cannot be guaranteed. All purchases will be followed by an order confirmation with estimated ship date and you will be notified if stock is unavailable. All orders for healthcare products placed after January 24, 2020 are non-cancellable and non-returnable. Thank you for your continued cooperation and partnership.

N N-Dimethylacetamide Reagentplus &, 500ml, Case/6

Synonym: DMAc

  • CAS Number 127-19-5
  • Linear Formula CH3CON(CH3)2
  • Molecular Weight 87.12
  • Beilstein/REAXYS Number 1737614
  • EC Number 204-826-4
  • MDL number MFCD00008686
  • eCl@ss 39031204
  • PubChem Substance ID 329751718
grade ReagentPlus
vapor density 3 (vs air)
vapor pressure

2 mmHg ( 25 °C)

4 mmHg ( 38 °C)

assay ≥99%
autoignition temp. 914 °F
expl. lim. 

1.8 %, 100 °F

11.5 %, 160 °F

refractive index  n20/D 1.437 (lit.)
bp 164.5-166 °C (lit.)
mp −20 °C (lit.)
density 0.937 g/mL at 25 °C (lit.)

General description

N,N-Dimethylacetamide (DMAc) is widely used to compose the solvent mixtures for cellulose. Static and dynamic light scattering studies of the cellulose dissolved in varying concentrations of DMAc/LiCl mixtures have been reported.


N,N-Dimethylacetamide (DMAc) has been employed as an organic solvent for the liquid-phase exfoliation of pristine graphene from bulk graphite. It may be used to compose the solvent system along with lithium chloride (LiCl) for the dissolution of commercial rayon grade cellulose. DMAc/LiCl solvent mixtures have been used for the preparation of chitin, cellulose and polyimide fibers and films.

N,N-Dimethylacetamide may be used in the preparation of α-lithio N,N-dimethylacetamide. DMAc along with palladium chloride forms an efficient catalytic system for the oxidation of several internal olefins to carbonyl compounds without undergoing isomerization.

Safety Information


Signal word Danger

Hazard statements H312 + H332-H319-H360D
Precautionary statements P201-P261-P280-P305 + P351 + P338-P308 + P313
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
WGK Germany 2
RTECS AB7700000
Flash Point(F) 147.2 °F
Flash Point(C) 64 °C


Safety Data Sheet


Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not work for, and ship to, a registered laboratory or research facility. Not for topical applications. An official Declaration of Use form may be required.

Most chemicals cannot be expedited.

This item has a Haz-Mat shipping fee built into the price. Fee is applicable only to the first item purchased. Additional HazMat items will be discounted automatically in the shopping cart. HazMat items always require special DOT handling and in rare cases may incur additional fees not levied prior to checkout. Request a quote for the most accurate pricing.

WARNING: This product can expose you to chemicals which are known to the State of California to cause cancer and reproductive harm. Prop 65 Warning

Please note: This product is not returnable.

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