Tetrahydrofuran (No BHT), HPLC/Spectro Grade, 4 Liter Bottles, case/4

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4 liter / 1 gallon
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HPLC/Spectro grade Tetrahydrofuran, inhibitor-free, in 4 liter glass bottles (16 liters total).

Tetrahydrofuran is a clear colorless liquid with an ethereal odor. It is used as a polar aprotic solvent and in gel permeation chromatography. THF tends to form shock-sensitive peroxides on storage so it is often sold inhibited with BHT, but this product has no BHT and is uninhibited. Tetrahydrofuran (THF) is an organic compound with the formula (CH2)4O. It has a role as a polar aprotic solvent. It is a member of oxolanes, a saturated organic heteromonocyclic parent, a cyclic ether and a volatile organic compound. Tetrahydrofuran (THF) is a contaminant of exposure and appears in human biofluids.

"HPLC/Spectroscopic grade" is a purified grade of solvent filtered to 0.2 micron and UV transparent for most LC and spectroscopy usage. See specifications for transparency range.

  • Description: Tetrahydrofuran
  • Chemical Formula: C4H8O
  • SDS: M0191
  • Melting Point: -108.3°C
  • Boiling Point: 66°C
  • Flash Point: -14°C
  • Formula Weight: 72.11
  • CAS No: 109-99-9
  • NFPA: 3-21
  • Density: 0.8892

Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not work for, and ship to, a registered laboratory or research facility. Not for topical applications. An official Declaration of Use form may be required.

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Test Name Limits
Assay (by GC-FID)
(Corrected for Water)
Min 99.8 %
Color Max 10 APHA
(as Hydrogen peroxide at time of packaging)
Max 0.015 %
Residue after Evaporation Max 5 ppm
(by KF coulometer)
Max 0.03 %
Titratable Acid Max 0.0008 meq/g
Optical Absorbance at  
212 nm Max 1.00 AU
225 nm Max 0.50 AU
250 nm Max 0.17 AU
350 nm Max 0.01 AU

The Food and Drug Administration (FDA) has announced recommendations to revise the permitted daily exposures for THF, and so has the International Conference on Harmonization. THF oxidizes readily, which can lead to instability and result in cytotoxicity. It is a colorless low-viscosity liquid with a smell similar to diethyl ether and is one of the most polar ethers. Tetrahydrofuran is essentially considered in occupational toxicology, and acute poisoning cases are extremely rare. THF is often used for hydroborations used to synthesize primary alcohols. THF is often used as a solvent for Grignard reagents because of the oxygen atom's ability to coordinate to the magnesium ion component of the Grignard reagent (an organometallic chemical reaction involving alkyl- or aryl-magnesium halides). THF is often used in polymer science. For example, it can be used to dissolve rubber prior to determining its molecular mass using gel permeation chromatography.

WARNING: This product can expose you to chemicals which are known to the State of California to cause cancer and reproductive harm. Prop 65 Warning

Please note: This product is not returnable.

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